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KMID : 0363620090300020079
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Journal of Korean Oriental Medicine
2009 Volume.30 No. 2 p.79 ~ p.87
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Inhibitory Effect of Respective Herbs in Cheonggugamrosu on Oral Malodor Using Malodor Modeling of the Salivary Sediment System
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Kim Jin-Sung
Park Jae-Woo
Yoon Seong-Woo
Ryu Bong-Ha
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Abstract
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Objective: This study assessed five respective herbs in Cheonggugamrosu (CGGRS) for ability to inhibit malodor in vitro.
Methods: We used malodor modeling of the salivary sediment system. Incubation mixtures were prepared with sediment at 16.7% (v/v), amino acids (cysteine and tryptophan) at 6mM and either herb extract at 1% (w/v) or water as control. Mixtures were incubated at 37℃ and odor was monitored organoleptically and for volatile sulfur compounds with the Halimeter. Indole/skatole was determined by Kovac’s colorimetric method.
Results: Two of the herbs, Caryophilli Flos and Glycyrrhizae Radix, had inhibitory effect on malodor generation. Both of them significantly reduced VSC, organoleptic odor and indole/skatole formation (p<0.05).
Conclusions: We found Caryophilli Flos and Glycyrrhizae Radix played a main role in CGGRS. Both herbs have potential as effective anti-malodor agents and this suggests they are worthy of further exploration.
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KEYWORD
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oral malodor, salivary sediment system, Cheonggugamrosu, Caryophilli Flos, Glycyrrhizae Radix
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